Basic Bioreactor DesignBased on a graduate course in biochemical engineering, provides the basic knowledge needed for the efficient design of bioreactors and the relevant principles and data for practical process engineering, with an emphasis on enzyme reactors and aerated reactors for microorganisms. Includes exercises, |
Contents
Introduction | 3 |
Basics | 25 |
Balances | 27 |
Yield | 49 |
Kinetics | 66 |
Stability | 89 |
Flow Flooding Dispersion | 102 |
Medium | 120 |
Mass Transfer | 234 |
Foam | 272 |
Heat Transfer | 291 |
Power Consumption | 301 |
Reaction Engineering Integration | 315 |
Macrokinetics Particle Level | 317 |
Apparent Stability | 340 |
Macrokinetics Reactor Level | 368 |
Shear | 134 |
Reactor Engineering | 179 |
Mixing | 181 |
HoldUp | 218 |
Process Engineering | 399 |
List of Symbols | 449 |
Index | 459 |
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Common terms and phrases
aerobic air lift anaerobic antifoam applied assumed batch biocatalyst particle biomass bioreactor Biotechnol broth bubble column bubble diameter calculated Chapter Chem circulation coalescing constant Croughan CSTR decrease defined density dispersion effectiveness factor enthalpy enzyme enzyme kinetics equation equilibrium Example external diffusion limitation fed-batch fermenter film first-order fluid foam gas flow rate gas phase given in Fig growth rate heat transfer Heijnen hold-up values ideally mixed immobilized biocatalyst impeller inactivation increase layer liquid velocity loop mass transfer measured method Michaelis-Menten kinetics microcarriers mol m-3 mol s-1 noncoalescing overall yield packed bed parameters plug-flow reactor Porec power consumption pressure production rate protein reaction Riet riser shear rate shear stress shows sparger specific growth rate stability stirred vessel stirrer power Substitution substrate substrate concentration surface temperature Tramper transfer coefficient turbine stirrer turbulent Umax viscosity zero