MicroRNA in CancerSuresh Alahari The field of microRNA biology is really emerging in the last couple of years. Several investigators highlighted the importance of miRNAs in cancer. Although there is so much literature on microRNAs exist, a comprehensive book is still not available. Thus this book will be a great use to the scientists in the field of cancer biology. In addition, this book will be a good source of information for undergraduate, graduate students who want to develop their research careers in cancer biology. |
Contents
| 1 | |
Function of miRNAs in Tumor Cell Proliferation | 13 |
MicroRNAs in Cancer Stem Cells | 29 |
MicroRNAs in the Pathogenesis of Viral Infections and Cancer | 43 |
Oncogenic microRNAs in Cancer | 63 |
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Common terms and phrases
Acad Sci U S A activity acute lymphoblastic leukemia acute myeloid leukemia apoptosis assay Bartel DP binding biogenesis Biol breast cancer breast cancer cells Calin Cancer Res cancer stem cells carcinoma cell cycle cell proliferation cellular Chen chromosome chronic lymphocytic leukemia cluster Croce CM croRNAs deletions Dicer differentiation down-regulated Drosha encoded enoxacin epigenetic epithelial gene expression Genet genomic human cancer identified induced inhibitors inhibits invasion and metastasis kinase levels luciferase lung cancer lymphoma mature miRNA metastasis metastatic mice microRNAs miRNA miRNA expression miRNA function miRNA regulation Mol Cell mouse mRNA mutations Natl Acad Sci non-coding RNAs normal oncogenic oncogenic microRNAs overexpression PDCD4 phenotype pre-miRNAs Proc Natl Acad prognosis promote prostate cancer protein region repression role sequence signaling silencing siRNA small molecule small RNAs specific suppression target mRNAs therapeutic transcription factor transfected treatment tumor cell tumor growth tumor suppressor upregulated viral virus vivo Wang Zhang