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Handbook of Mouse Mutations With Skin and Hair Abnormalities:

Animal Models and Biomedical Tools
Front Cover
John P. Sundberg
0 Reviews
CRC Press, 1994 - Medical - 544 pages
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects.

The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
  

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Selected pages

Contents

Hair Follicle Stem Cells
30
The Mouse Skin as a Model for Chemical Carcinogenesis
39
Viral Induced Skin Tumors in Mice
47
Hair Types and Subtypes in the Laboratory Mouse
57
Growth Factors and Cutaneous Pathology
69
Transgenic Mice with Cytokine Mutations Affecting the Skin
81
Epidermal Keratins
95
Hair Follicle Keratins
105
The Ferrochelatase Deficiency Fechm1ps Mutation
247
The Flaky Tail ft Mutation Chromosome 3
269
The Greasy Gs Mutation Chromosome X
285
The Hair Patches Hpt Mutation Chromosome 4
313
The Ichthyosis ic Mutation Chromosome 1
327
The Lustrous It Mutation Chromosome 11
343
The mammalian hair cycle is a fascinating example of tissue development and remodeling that
345
Mottled Mo Blotchy Moht Brindled Mohr
359

Keratinocyte Cultures as Models for Dermatological Disease
117
Mouse Mutations with Endocrine Functional Consequences
129
the Search for
143
ANIMAL MODELS OF GENETIC BASED SKIN DISEASES
155
The Angora go Mutation Chromosome 5
165
The Asebia ab ah1 Mutations Chromosome 19
171
The Atrichosis at Mutation Chromosome 10
179
The BarePatches Bpa Mutation Chromosome X
193
The Caracul Ca and Cad Mutations Chromosome 15
211
The CurlyWhiskers cw Mutation Chromosome 9
231
The Nude nu and Streaker nuar Mutations Chromosome 11
379
The Repeated Epilation Er Mutation Chromosome 4
399
The Satin sa Mutation Chromosome 13
413
The Shaven Sha Mutation Chromosome 15
431
The SparseCoat spc Mutation Chromosome 14
447
The TightSkin Tsk Mutation Chromosome 2
463
Introduction
483
Alopecia Areata in Aging C3HHeJ Mice
499
Index
533
Copyright

Common terms and phrases

allele alopecia alopecia areata anagen ANALOGOUS ANIMAL DISEASES ANALOGOUS HUMAN DISEASE animal model autosomal recessive AVAILABILITY OF MICE background BIOCHEMICAL ABNORMALITIES Biol carcinogenesis centimorgans centromere coat collagen CRC Press crinkled culture cutaneous days of age defect deficiency Dermatol dermis differentiation downless effects Embryo epidermal epithelial expression flaky skin follicular function genetic GROSS LESIONS growth factor hair cycle hair follicles hair growth hair shaft hairless mouse heterozygous homozygous house mouse ichthyosis immunodeficiency Immunological and Biochemical inbred strain Invest Jackson Laboratory keratin keratinocytes Laboratory Mouse littermate controls locus melanocytes MICROSCOPIC LESIONS motheaten mouse Chromosome mouse mutation Mouse News Lett mouse skin mutant genes mutant mice normal nude mice outer root sheath papillomas Pathol pelage pelage hairs phenotype pigment proteins psoriasis receptor rhino scurfy sebaceous glands severe combined immunodeficiency Shultz spontaneously stem cells studies syndrome tabby tail TGFa tissue transgenic transgenic mice tumor vibrissae vitiligo vitro

References to this book

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From Google Scholar

Asebia-2J (Scd1 ab2J): A New Allele and a Model for Scarring Alopecia
John P Sundberg, Dawnalyn Boggess, Beth A Sundberg, Ken Eilertsen, Satish Parimoo, Mario Filippi ... - 2000 - American Journal of Pathology
Vitamin D3 receptor ablation sensitizes skin to chemically induced ...
Glendon M Zinser, John P Sundberg, JoEllen Welsh - 2002 - Carcinogenesis
NF-κB transmits Eda A1/EdaR signalling to activate Shh and cyclin ...
Ruth Schmidt-Ullrich, Desmond J Tobin, Diana Lenhard, Pascal Schneider, Ralf Paus, Claus Scheidereit - 2006 - Development
Molecular Histology in Skin Appendage Morphogenesis
RANDALL B WIDELITZ, TING-XIN JIANG, ALEXANDER NOVEEN, SHEREE A TING-BERRETH, ERIC YIN, HAN-SUNG ... - 1997 - MICROSCOPY RESEARCH AND TECHNIQUE
All Scholar search results »

References from web pages

Skinbase - Mutant Mouse Skin Database: Funded by the North ...
Sundberg JP, The Flaky Tail (ft) Mutation, Chromosome 3, In: Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical ...
eulep.pdn.cam.ac.uk/ ~skinbase/ mutant_images.php?mutant=Matted_(ma)_and_Flaky_Tail_(ft)_Mutant_Mice_Chr3

Journal of Investigative Dermatology - Abstract of article: Mouse ...
Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools CRC Press, Boca Raton, FL, pp 217–220, 1994; Lane, ...
www.nature.com/ jid/ journal/ v106/ n2/ abs/ 5610647a.html

Dermatologic Clinics : MOUSE MODELS FOR THE STUDY OF HUMAN HAIR ...
Quick Search, Title, abstract, keywords, Author, eg js smith. Search tips (Opens new window), Journal/book title, Volume, Issue, Page, Clear all fields ...
linkinghub.elsevier.com/ retrieve/ pii/ S0733863505703892

Mutations in Gasdermin 3 Cause Aberrant Differentiation of the ...
Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools. New York: CRC Press, 1994a. •, Sundberg JP: The Rex (Re), ...
www.blackwell-synergy.com/ links/ doi/ 10.1111/ j.0022-202X.2005.23623.x/ abs/

European Journal of Dermatology
Handbook of mouse mutations with skin and hair abnormalities: animal models and biomedical tools. Edited by Sundberg JP. Boca Raton, FL, CRC Press, ...
www.jle.com/ en/ revues/ medecine/ ejd/ e-docs/ 00/ 01/ 88/ 9B/ article.md

Agris Search Results
Titles, Handbook of mouse mutations with skin and hair abnormalities: animal models and biomedical tools. Personal Authors, Sundberg, jp ...
www.fao.org/ agris/ search/ display.do;jsessionid=4646085BCAC73B6FD2F1AF84E50C994A?f=./ 1995/ v2116/ US9525666.xml;US9525666

Asebia-2J (scd1ab2j): A New Allele and a Model for Scarring Alopecia
Handbook of Mouse Mutations with Skin and Hair Abnormalities. Animal Models and Biomedical Tools. Boca Raton, FL, CRC Press, 1994, pp 171–177. ...
www.pubmedcentral.nih.gov/ articlerender.fcgi?artid=1850069

Springer Protocols: Abstract: Experimental Induction of Human ...
Sundberg, jp (1994) The nude (nu) and streaker (nustr) mutations, chromosome 11, in Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal ...
www.springerprotocols.com/ Abstract/ doi/ 10.1385/ 1-59259-145-0:71

Asebia-2J (scd1ab2j): A New Allele and a Model for Scarring ...
Handbook of Mouse Mutations with Skin and Hair Abnormalities. Animal Models and Biomedical Tools. Boca Raton, FL, CRC Press, 1994, pp 171–177 ...
ajp.amjpathol.org/ cgi/ content/ full/ 156/ 6/ 2067

Desmoglein 3 anchors telogen hair in the follicle
INTRODUCTION. Desmoglein 3 (Dsg3) is a desmosomal transmembrane. glycoprotein that belongs to the cadherin superfamily of cell ...
jcs.biologists.org/ cgi/ reprint/ 111/ 17/ 2529.pdf

Bibliographic information

QR code for Handbook of Mouse Mutations With Skin and Hair Abnormalities
TitleHandbook of Mouse Mutations With Skin and Hair Abnormalities: Animal Models and Biomedical Tools
CRC series in dermatology
CRC series in dermatology: clinical and basic science
Dermatology (Boca Raton)
Dermatology Series
Studies in Advanced Mathematics
EditorJohn P. Sundberg
Editionillustrated
PublisherCRC Press, 1994
ISBN0849383722, 9780849383724
Length544 pages
Subjects ›  › 

Medical / Dermatology
Medical / Research
Science / Life Sciences / Genetics & Genomics
  
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