DermatotoxicologyKlaus Peter Wilhelm, Hongbo Zhai, Howard I. Maibach Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated |
Contents
| 1 | |
| 5 | |
| 31 | |
| 39 | |
| 51 | |
| 63 | |
ShortTerm Exposure Lag Time Multiple Exposures Model Variations and Absorption from Clothing | 71 |
| 81 | |
| 497 | |
| 505 | |
| 517 | |
| 525 | |
| 537 | |
| 547 | |
| 551 | |
| 561 | |
| 87 | |
| 95 | |
| 101 | |
| 107 | |
| 125 | |
| 139 | |
| 155 | |
| 159 | |
| 169 | |
| 175 | |
| 189 | |
| 201 | |
| 209 | |
| 215 | |
| 227 | |
| 235 | |
| 241 | |
| 245 | |
| 259 | |
| 269 | |
| 279 | |
| 283 | |
| 295 | |
| 299 | |
| 303 | |
| 307 | |
| 311 | |
| 317 | |
| 327 | |
| 339 | |
| 343 | |
| 347 | |
| 359 | |
| 373 | |
| 377 | |
| 383 | |
| 391 | |
| 401 | |
| 415 | |
| 417 | |
| 423 | |
| 431 | |
| 437 | |
| 443 | |
| 463 | |
| 469 | |
| 481 | |
| 485 | |
| 569 | |
| 577 | |
| 581 | |
| 587 | |
| 613 | |
| 617 | |
| 621 | |
| 629 | |
| 659 | |
| 669 | |
| 673 | |
| 689 | |
| 697 | |
| 707 | |
| 713 | |
| 721 | |
| 725 | |
| 733 | |
| 743 | |
| 749 | |
| 759 | |
| 765 | |
| 773 | |
| 781 | |
| 787 | |
| 795 | |
| 807 | |
| 839 | |
| 851 | |
| 865 | |
| 873 | |
| 881 | |
| 891 | |
| 897 | |
| 911 | |
| 919 | |
| 923 | |
Reproducibility for Fifty Chemicals Tested with Two Protocols | 927 |
| 945 | |
Nonimmunologic Contact Urticaria Induced by Hexyl Nicotinate | 951 |
Chapter 105 Is Contact Allergy Lifelong in Humans? An Overview of PatchTest FollowUps | 955 |
Overview of Tandem Irritation Studies | 959 |
A Conundrum? | 967 |
Overview | 971 |
Appendix | 981 |
Index | 985 |
Back cover | 1017 |
Other editions - View all
Common terms and phrases
Acad acid Acta activity allergic contact dermatitis animals application Arch assessment barrier function Basketter Berardesca blacks Caucasian cells ceramide Chem chemical chlorhexidine chloride Clin clinical compounds concentration contact allergens contact urticaria cosmetics cutaneous cytokines Derm Dermatol Dermatology diffusion dose drug delivery ECVAM eczema effects enhancement epidermal erythema evaluation exposure factors forearm guinea pig histamine human skin hypersensitivity increased induced Invest iontophoresis irritant dermatitis keratinocytes Kimber Kligman lipid lymph node lymph node assay Maibach measured melanosomes membrane metabolism method mice Monteiro-Riviere nickel occlusion parameters patch test patients penetration percutaneous absorption perfused permeability petrolatum Pharm Pharmacol phototoxic potential protein reactions reactivity receptor response retinoids Riviere skin barrier skin irritation skin sensitization sodium lauryl sodium lauryl sulfate stratum corneum studies sulfate surfactants syndrome tape stripping TEWL tion tissue topical toxicity Toxicol Toxicology transdermal tretinoin vehicle Venereol vitro vivo Wester
Popular passages
Page 505 - The molecular and cellular mechanisms that result in the induction and elicitation of contact allergy have been reviewed extensively elsewhere (Grabbe and Schwarz, 1998; Kimber etal., 2002; Kimber and Dearman, 2002).
Page 4 - A comparison of amphotericin B alone and combined with flucytosine in the treatment of cryptococcal meningitis. N Engl J Med 1979; 301:126-31.