Bioorganic and Medicinal Chemistry of Fluorine
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Contents
| 1 | |
2 Overview on the Preparation of Fluorinated Compounds | 23 |
3 Effects of Fluorine Substitution on Biological Properties | 72 |
4 Fluorinated Analogues of Natural Products | 99 |
5 Fluorinated Derivatives of αAmino Acids and Proteins | 146 |
Other editions - View all
Bioorganic and Medicinal Chemistry of Fluorine Jean-Pierre Bégué,Daniele Bonnet-Delpon No preview available - 2008 |
Bioorganic and Medicinal Chemistry of Fluorine Jean-Pierre Bégué,Daniele Bonnet-Delpon No preview available - 2008 |
Common terms and phrases
ACS Symposium Series activity affinity alcohols aldehyde alkyl amine amino acids anion antagonist aromatic biological Bioorg BnO BnO Bonnet-Delpon carbanions CF 3 CF CF2H CF3 group CF3 OH CH2F Chapter Chem chiral clinical trials CO2Et CO2H COOEt COOH DAST derivatives difluorocarbene difluorophosphonates double bond Drugs Fut effect electrophilic electrophilic fluorination enol enzyme enzyme inhibitors ester ethyl F F F Figure fluoral fluorinated analogues fluorinated compounds fluorine atoms Fluorine Chem fluoroalkyl fluoroquinolones hydrogen bonds hydroxyl inhibition inhibitors J.P. B egu ketones medicinal chemistry metabolism moiety molecules nonfluorinated nucleophilic nucleosides OH CF3 OH F F OH OH OH OH OH oxidation Pantoprazole peptidic perfluoroalkyl Phase precursor prepared presence of fluorine protease protein radical reaction reactivity reagent receptor stability substitution substrate Synthesis Synthons Tetrahedron Lett treatment trifluoroethanol trifluoromethyl trifluoromethyl ketones Trifluridine Washington DC