Skin Barrier

Front Cover
Peter M. Elias, Kenneth R. Feingold
CRC Press, Jun 27, 2013 - Medical - 632 pages
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A must-have reference for any researcher or scientist interested in cutaneous protective mechanisms, this guide provides expertly researched chapters on every aspect of stratum corneum structure, function, and development, as well as detailed sections on barrier-repair strategies and the role of barrier function in diseases such as atopic dermatitis, psoriasis, and ichthyosis.
  

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Contents

Definitions and Broad Concepts
1
Integrative Aspects
5
3 A Brief History of How the Dead Stratum Corneum Became Alive
15
From Saran Wrap to Biosensor
25
5 Biochemistry of Human Stratum Corneum Lipids
33
Function Origins and Therapeutic Applications
43
7 Structure of the Skin Barrier
65
8 Cornified Envelope and CorneocyteLipid Envelope
97
19 The Role of the Primary Cytokines TNF IL1 and IL6 in Permeability Barrier Homeostasis
305
Epidermal Liposensors
319
21 Permeability Barrier Homeostasis
337
22 Cutaneous Barriers in Defense Against Microbial Invasion
363
23 The Epidermal Antioxidant Barrier
379
24 Sources and Role of Stratum Corneum Hydration
399
25 Vitamin D and the Epidermis
427
26 Diseases That Affect Barrier Function
447

9 Profilaggrin and the Fused S100 Family of CalciumBinding Proteins
111
10 The Role of Keratins in Epithelial Homeostasis
141
Pivotal Actors in the Stratum Corneum Cohesion and Desquamation
171
Role of Tight Junctions
191
13 What Makes a Good Barrier? Adaptive Features of Vertebrate Integument
211
Measurement Origins and Functions
223
The Final Steps in Barrier Formation
231
16 The Epidermal Lamellar Body as a Multifunctional Secretory Organelle
261
17 Skin Structural Development
273
18 Epidermal Calcium Gradient and the Permeability Barrier
289
27 Pathogenesis of the Barrier Abnormalities in Disorders of Cornification
469
28 Pathogenesis of Desquamation and Permeability Barrier Abnormalities in RXLI
511
29 Prevention and Repair of Barrier Disruption in Occupational Dermatology
519
Basis for Functional Abnormalities
535
The Psychosensory Interface
553
32 The Stratum Corneum of the Epidermis in Atopic Dermatitis
569
Fixing the BarrierTheory and Rational Deployment
591
Index
601
Back cover
613
Copyright

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References from web pages

Epidermal Skin Barrier: Implications for the Wound Care ...
Skin Barrier. Principles of Percutaneous Absorption. Basel, Switzerland: Karger; 1996. 4. Ellas PM. The epidermal permeability barrier: from the early days ...
findarticles.com/ p/ articles/ mi_qa3977/ is_200410/ ai_n9461227/ pg_8

Skin barrier structure and function and their relationship to ...
The purpose of the present study was to assess the function and structure of the skin barrier in patients with ESRD and to correlate any abnormalities with ...
ndt.oxfordjournals.org/ cgi/ content/ full/ gfm375v1

Lipopenia and Skin Barrier Abnormalities in DGAT2-deficient Mice ...
Lipopenia and Skin Barrier Abnormalities in DGAT2-deficient Mice*. Scot J. Stone {ddagger} § , Heather M. Myers {ddagger} , Steven M. Watkins¶, Barbara E. ...
www.jbc.org/ cgi/ content/ abstract/ 279/ 12/ 11767

Skin barrier structure, function and formation ± learning from ...
the skin barrier. In fact, an up to eightfold composi-. tional di¡erence (in wt%) for single ..... Central problems for the understanding of skin barrier ...
www.blackwell-synergy.com/ doi/ pdf/ 10.1046/ j.1467-2494.2003.00187.x

Lipid defect underlies selective skin barrier impairment of an ...
Comparison of these animal models illustrates how impairment of the skin barrier by two genetically distinct mechanisms leads to innate immune responses, ...
www.jcb.org/ cgi/ content/ full/ 175/ 4/ 661

Development of ichthyosiform skin compensates for defective ...
Lipopenia and Skin Barrier Abnormalities in DGAT2-deficient Mice J. Biol. Chem., March 19, 2004; 279(12): 11767 - 11776. [Abstract] [Full Text] [PDF] ...
www.jci.org/ cgi/ content/ abstract/ 109/ 2/ 243

Skin Barrier edited by Peter M. Elias
Skin Barrier provides every aspect of stratum corneum structure, function, and development, as well as detailed sections on barrier-repair strategies and ...
www.chipsbooks.com/ skinbarr.htm

accessmedicine - Content
Epidermal Proliferation and Differentiation in Skin Barrier Function ... Pathologic Skin Barriers: Skin Barrier Function in Dermatoses ...
www.accessmedicine.com/ content.aspx?aid=2977697

Advances in Skin & Wound Care - Fulltext: Volume 17(8) October ...
This first article in a 2-part series on the epidermal skin barrier will examine the anatomy and development of the epidermis and stratum corneum, ...
www.aswcjournal.com/ pt/ re/ advswc/ fulltext.00129334-200410000-00011.htm;jsessionid=H0jHhLTnvLt3DlJvq5nGN36QHmVVVpN6M0...

Clinical Obstetrics and Gynecology - Fulltext: Volume 50(3 ...
A decline in skin barrier function is the essence of menopausal skin change at ... With the close proximity of the rectum, vulvar skin-barrier decline would ...
www.clinicalobgyn.com/ pt/ re/ clnobgyn/ fulltext.00003081-200709000-00017.htm;jsessionid=HBbWKl3KXJHrhbTW8HGRG9Sx8PVM21...

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