Chemical Warfare Agents: Toxicology and Treatment

Front Cover
Timothy T. Marrs, Robert L. Maynard, Frederick Sidell
John Wiley & Sons, Apr 4, 2007 - Medical - 750 pages
Chemical Warfare Agents, Second Edition has been totally revised since the successful first edition and expanded to about three times the length, with many new chapters and much more in-depth consideration of all the topics. The chapters have been written by distinguished international experts in various aspects of chemical warfare agents and edited by an experienced team to produce a clear review of the field.

The book now contains a wealth of material on the mechanisms of action of the major chemical warfare agents, including the nerve agent cyclosarin, formally considered to be of secondary importance, as well as ricin and abrin. Chemical Warfare Agents, Second Edition discusses the physico-chemical properties of chemical warfare agents, their dispersion and fate in the environment, their toxicology and management of their effects on humans, decontamination and protective equipment. New chapters cover the experience gained after the use of sarin to attack travellers on the Tokyo subway and how to deal with the outcome of the deployment of riot control agents such as CS gas.

This book provides a comprehensive review of chemical warfare agents, assessing all available evidence regarding the medical, technical and legal aspects of their use. It is an invaluable reference work for physicians, public health planners, regulators and any other professionals involved in this field.

Review of the First Edition:

"What more appropriate time for a title of this scope than in the post 9/11 era? ...a timely, scholarly, and well-written volume which offers much information of immense current and...future benefit."
—VETERINARY AND HUMAN TOXICOLOGY

 

Contents

1 Opinions of Chemical Warfare
1
2 The Physicochemical Properties and General Toxicology of Chemical Warfare Agents
21
3 Dispersion and Modelling of the Spread of Chemical Warfare Agents
67
4 The Fate of Chemical Warfare Agents in the Environment
89
5 Biological Markers of Exposure to Chemical Warfare Agents
127
6 Respiratory Protection
157
7 Responding to Chemical Terrorism Operational Planning and Decontamination
175
8 Toxicology of Organophosphate Nerve Agents
191
17 Pretreatment for Nerve Agent Poisoning
343
18 Gulf War Syndrome
355
19 Mustard Gas
375
20 Dermal Aspects of Chemical Warfare
409
21 Sulphur Mustard Injuries of the Skin Pathophysiology and Clinical Management of Chemical Burns
423
22 The Normal Bone Marrow and Management of ToxinInduced Stem Cell Failure
443
23 Organic Arsenicals
467
24 Phosgene
477

9 A History of Human Studies with Nerve Agents by the UK and USA
223
10 Nerve Agents LowDose Effects
241
11 Managing Civilian Casualties Affected by Nerve Agents
249
12 The Management of Casualties Following Toxic Agent Release The Approach Adopted in France
261
13 The Dark Morning The Experiences and Lessons Learned from the Tokyo Subway Sarin Attack
277
14 Atropine and Other Anticholinergic Drugs
287
15 Oximes
305
16 The Use of Benzodiazepines in Organophosphorus Nerve Agent Intoxication
331
25 Cyanides Chemical Warfare Agents and Potential Terrorist Threats
495
26 Riot Control Agents in Military Operations Civil Disturbance Control and Potential Terrorist Activities with Particular Reference to Peripheral Che...
543
27 Ricin and Abrin Poisoning
613
28 The Total Prohibition of Chemical Weapons
633
29 An AZ of Compounds of Interest in Relation to Chemical Warfare and Other Malevolent Uses of Poisons
663
Index
709
Copyright

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About the author (2007)

Timothy C. Marrs OBE. Edentox Associates, Edenbridge, Kent, UK; National Poisons Information Service Birmingham Centre, City Hospital, Birmingham, UK; University of Central Lancashire, Preston, UK.

Robert L. Maynard CBE. Air Pollution Unit, Health Protection Agency, London, UK.

Frederick R. Sidell †. Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.

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