Chemical Warfare Agents: Toxicology and Treatment

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Timothy T. Marrs, Robert L. Maynard, Frederick Sidell
John Wiley & Sons, Apr 4, 2007 - Medical - 750 pages
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Chemical Warfare Agents, Second Edition has beentotally revised since the successful first edition and expanded toabout three times the length, with many new chapters and much morein-depth consideration of all the topics. The chapters have beenwritten by distinguished international experts in various aspectsof chemical warfare agents and edited by an experienced team toproduce a clear review of the field.

The book now contains a wealth of material on the mechanisms ofaction of the major chemical warfare agents, including the nerveagent cyclosarin, formally considered to be of secondaryimportance, as well as ricin and abrin. Chemical WarfareAgents, Second Edition discusses the physico-chemicalproperties of chemical warfare agents, their dispersion and fate inthe environment, their toxicology and management of their effectson humans, decontamination and protective equipment. New chapterscover the experience gained after the use of sarin to attacktravellers on the Tokyo subway and how to deal with the outcome ofthe deployment of riot control agents such as CS gas.

This book provides a comprehensive review of chemical warfareagents, assessing all available evidence regarding the medical,technical and legal aspects of their use. It is an invaluablereference work for physicians, public health planners, regulatorsand any other professionals involved in this field.

Review of the First Edition:

"What more appropriate time for a title of this scope than inthe post 9/11 era? ...a timely, scholarly, and well-written volumewhich offers much information of immense current and…futurebenefit."
—VETERINARY AND HUMAN TOXICOLOGY

 

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Contents

1 Opinions of Chemical Warfare
1
2 The Physicochemical Properties and General Toxicology of Chemical Warfare Agents
21
3 Dispersion and Modelling of the Spread of Chemical Warfare Agents
67
4 The Fate of Chemical Warfare Agents in the Environment
89
5 Biological Markers of Exposure to Chemical Warfare Agents
127
6 Respiratory Protection
157
7 Responding to Chemical Terrorism Operational Planning and Decontamination
175
8 Toxicology of Organophosphate Nerve Agents
191
17 Pretreatment for Nerve Agent Poisoning
343
18 Gulf War Syndrome
355
19 Mustard Gas
375
20 Dermal Aspects of Chemical Warfare
409
21 Sulphur Mustard Injuries of the Skin Pathophysiology and Clinical Management of Chemical Burns
423
22 The Normal Bone Marrow and Management of ToxinInduced Stem Cell Failure
443
23 Organic Arsenicals
467
24 Phosgene
477

9 A History of Human Studies with Nerve Agents by the UK and USA
223
10 Nerve Agents LowDose Effects
241
11 Managing Civilian Casualties Affected by Nerve Agents
249
12 The Management of Casualties Following Toxic Agent Release The Approach Adopted in France
261
13 The Dark Morning The Experiences and Lessons Learned from the Tokyo Subway Sarin Attack
277
14 Atropine and Other Anticholinergic Drugs
287
15 Oximes
305
16 The Use of Benzodiazepines in Organophosphorus Nerve Agent Intoxication
331
25 Cyanides Chemical Warfare Agents and Potential Terrorist Threats
495
26 Riot Control Agents in Military Operations Civil Disturbance Control and Potential Terrorist Activities with Particular Reference to Peripheral Che...
543
27 Ricin and Abrin Poisoning
613
28 The Total Prohibition of Chemical Weapons
633
29 An AZ of Compounds of Interest in Relation to Chemical Warfare and Other Malevolent Uses of Poisons
663
Index
709
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About the author (2007)

  Timothy C. Marrs OBE. Edentox Associates, Edenbridge,Kent, UK; National Poisons Information Service Birmingham Centre,City Hospital, Birmingham, UK; University of Central Lancashire,Preston, UK.

Robert L. Maynard CBE. Air Pollution Unit, HealthProtection Agency, London, UK.

Frederick R. Sidell †. Institute of ChemicalDefense, Aberdeen Proving Ground, Maryland, USA.

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