The Resistance Phenomenon in Microbes and Infectious Disease Vectors: Implications for Human Health and Strategies for Containment: Workshop Summary

Front Cover
National Academies Press, Mar 26, 2003 - Medical - 333 pages

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

 

Contents

Summary and Assessment
1
1 Introduction
19
2 Microbe Resistance
44
3 Vector Resistance
79
4 The Economics of Resistance
107
5 Factors Contributing to the Emergence of Resistance
130
6 Emerging Tools and Technology for Countering Resistance
159
7 Strategies to Contain the Development and Consequences of Resistance
196
Appendix A
231
Appendix B
244
Appendix C Information Resources
249
Appendix D
256
A Review of the Literature and Exploration of Modelling CostEffectiveness
274
Appendix F A Public Health Action Plan to Combat Antimicrobial Resistance
279
Appendix G Forum Member Speaker and Staff Biographies
287
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