Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools

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CRC Press, May 19, 1994 - Medical - 560 pages
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Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects.

The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
 

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Contents

Chapter
30
Hair Follicle Stem Cells
37
INTRODUCTION
39
Chapter
43
Viral Induced Skin Tumors in Mice
47
Hair Types and Subtypes in the Laboratory Mouse
57
Growth Factors and Cutaneous Pathology
69
Chapter 48
75
ANIMAL MODELS OF GENETIC BASED SKIN DISEASES
155
The Angora go Mutation Chromosome 5
165
The Asebia ab ab Mutations Chromosome 19
171
The Crinkled cr Mutation Chromosome 13
221
Chromosome 18
247
by CRC Press Inc 29
345
Chromosome 6
351
Mutations Chromosome 11
407

Transgenic Mice with Cytokine Mutations Affecting the Skin
81
Epidermal Keratins
95
Hair Follicle Keratins
105
Keratinocyte Cultures as Models for Dermatological Disease
117
Mouse Mutations with Endocrine Functional Consequences
129
the Search for
143
Chromosome 16
423
Mutations Chromosome X
449
Introduction
483
Alopecia Areata in Aging C3HHe Mice
499
Index
533
Copyright

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