NMR of Proteins
Clore, A. M. Gronenborn
CRC Press, 1993 - Medical - 307 pages
This reference represents the most comprehensive and up-to-date collection of biological NMR literature. NMR of Proteins highlights recent advances in the field both with respect to methodology and applications. Four chapters deal with structure determinations of soluble proteins, including approaches for larger proteins, protein modules, and protein-ligand complexes. Other topics include structural studies on membrane proteins, NMR methodology, the investigation of dynamic properties, and protein folding studies. Contributors to this important volume are internationally known experts in their respective fields.
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Methodological advances in protein NMR A Bax
Determination of highresolution NMR structures of proteins
Multidimensional NMR studies
NMR studies of the structure and role of modules involved
NMR structural studies of membrane proteins S J Opella
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3D and 4D 3D NMR amide protons amino acid ascomycin atoms backbone bacteriorhodopsin bilayers binding Biochemistry Biol calculations carbon carboxyl Chem chemical shift Clore complex conformation constraints correlation coupling constants cross-peaks CsA/CyP cyclophilin dipolar distance geometry distance restraints domain experimental fd coat protein Fesik FKBP folded frequencies helices helix hydrogen bonds Ikura interactions internal motions labelled larger proteins ligand lysozyme Magn measured membrane proteins methods methyl micelles mobility model-free module molecular dynamics molecules mutant NMR experiments NMR spectroscopy NMR structures NMR studies NOESY nuclear magnetic resonance observed obtained Opella order parameters orientation peptide pKa value plastocyanin protein structure receptor refinement relaxation parameters relaxation rates residues samples secondary structure shown in Figure side-chain SNase solid-state NMR solution NMR solution structure spectral density spectral density function spin systems structure determination T4 lysozyme three-dimensional structure tion vector Wuthrich X-ray structure