Biology Is Technology: The Promise, Peril, and New Business of Engineering Life

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Harvard University Press, Apr 15, 2011 - Science - 290 pages
“Essential reading for anyone who wishes to understand the current state of biotechnology and the opportunities and dangers it may create.” —American Scientist

Technology is a process and a body of knowledge as much as a collection of artifacts. Biology is no different—and we are just beginning to comprehend the challenges inherent in the next stage of biology as a human technology. It is this critical moment, with its wide-ranging implications, that Robert Carlson considers in Biology Is Technology. He offers a uniquely informed perspective on the endeavors that contribute to current progress in this area—the science of biological systems and the technology used to manipulate them.

In a number of case studies, Carlson demonstrates that the development of new mathematical, computational, and laboratory tools will facilitate the engineering of biological artifacts—up to and including organisms and ecosystems. Exploring how this will happen, with reference to past technological advances, he explains how objects are constructed virtually, tested using sophisticated mathematical models, and finally constructed in the real world.

Such rapid increases in the power, availability, and application of biotechnology raise obvious questions about who gets to use it, and to what end. Carlson’s thoughtful analysis offers rare insight into our choices about how to develop biological technologies and how these choices will determine the pace and effectiveness of innovation as a public good.
 

Contents

1 What Is Biology?
1
2 Building with Biological Parts
8
3 Learning to Fly or Yeast Geese and 747s
20
4 The Second Coming of Synthetic Biology
33
5 A Future History of Biological Engineering
50
6 The Pace of Change in Biological Technologies
63
7 The International Genetically Engineered Machines Competition
81
8 Reprogramming Cells and Building Genomes
97
10 The Sources of Innovation and the Effects of Existing and Proposed Regulations
131
11 Laying the Foundations for a Bioeconomy
150
12 Of Straitjackets and Springboards for Innovation
178
13 OpenSource Biology or Open Biology?
200
14 What Makes a Revolution?
218
Afterword
240
Notes
243
Index
267

9 The Promise and Peril of Biological Technologies
108

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About the author (2011)

Rob Carlson is a Senior Associate at Bio Economic Research Associates and Principal at Biodesic. He has worked to develop new biological technologies in both academic and commercial environments, focusing on molecular measurement and microfluidic systems.

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