Pathology of the Human Placenta

Front Cover
Springer Science & Business Media, Mar 23, 2000 - Medical - 950 pages
Most obstetricians and pediatricians would agree that the examination of the pla centa often helps to explain an abnormal neonatal outcome. As early as in 1892, Bal lantyne wrote that A diseased faetus without its placenta is an imperfect specimen, and a description of a foetal malady, unless accompanied by a notice of the placental condition, is incomplete. Deductions drawn from such a case cannot be considered as conclusive, for in the missing placenta or cord may have existed the cause of the disease and death. During intrauterine life the foetus, the membranes, the cord and the placenta form an organic whole, and disease of any part must react upon and affect the others. Similar thoughts were succinctly detailed in Price's discussion of his concept of the "prenatal biases" as they affected twins. His contribution also admonishes us that placental study is a sine qua non for a more perfect understanding of fetal develop ment (1950). Despite all this understanding of the past and appreciation for placen tal disease, great resistance still exists to performing the task of placental examination routinely. For many pathologists, therefore, the placenta has remained a mysterious organ.
 

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Contents

Preface
1
Macroscopic Features of the Delivered Placenta
13
Placental Types
29
Early Development of the Human Placenta
42
Basic Structure of the Villous Trees
50
Endoplasmic Reticulum
57
Villous Cytotrophoblast Langhans Cells
65
Syncytial Fusion and Trophoblast Turnover
72
Thrombosis of the Placental Vascular Tree
379
References
386
Placental Shape Aberrations
399
Histopathological Approach to Villous Alterations
419
Classification of Villous Maldevelopment
437
Preplacental Hypoxia
452
Erythroblastosis Fetalis and Hydrops Fetalis
461
Transplacental Hemorrhage Cell Transfer Trauma
492

Trophoblastic Basement Membrane
78
Other Free Connective Tissue Cells
89
References
96
Characterization of the Developmental Stages
155
Nonvillous Parts and Trophoblast Invasion
171
Fibrinoid
196
Trophoblast Invasion as a Result of DeciduoTrophoblastic
202
Chorionic Plate
208
Basal Plate
214
Septa Cell Islands and Cell Columns
226
Involution of Implantation Site and Retained Placenta
273
Anatomy and Pathology of the Placental Membranes
281
Anatomy and Pathology of the Umbilical Cord and Major
335
Spiral Turns of the Cord
346
Placental Surface Vessels
359
Placental Transfusion
366
Varices and Aneurysms
373
Fetal Storage Disorders
516
Diabetes
523
Hypertensive Disorders
542
Lupus Erythematosus and Lupus Anticoagulant
562
References
571
Infectious Diseases
591
Abortion Placentas of Trisomies and Immunological
685
Induced Abortions
695
Trisomic Placentas
703
References
709
Molar Pregnancies
718
Trophoblastic Neoplasm
754
Benign Tumors and Chorangiosis
778
Multiple Pregnancy
790
Legal Considerations
903
Glossary
917
Copyright

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