Retinoids and Carotenoids in DermatologyAnders Vahlquist, Madeleine Duvic This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of retinoid therapy, this source also addresses topics outside of dermatology, such as vitamin A nutrition, and the role of antioxidants in aging, metabolic activation, and cellular signaling. With chapters by internationally recognized authorities in specialties ranging from biochemistry and nutrition to molecular biology and clinical science, this source will stand as the only up-to-date source on the topic. |
Contents
Implications | 27 |
From Vitamin A in Human Epidermis | 55 |
Recent Studies on the Pharmacokinetics | 69 |
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Acad Dermatol Acad Sci acitretin acne vulgaris activity adapalene all-trans retinoic acid antioxidant apoptosis Arch Dermatol B-carotene basal beta-carotene bexarotene binding Biochem Biol Chem carcinoma carotene carotenoids cells cellular Clin clinical collagen combination concentrations cream cutaneous T-cell lymphoma decreased dermal Dermatology dietary disease disorders dose drug Duvic efficacy enzymes epidermis etretinate expression factor fibroblasts function gene growth heterodimers human skin hyperkeratosis ichthyosis increased induced inhibition Invest Dermatol isotretinoin keratinization keratinocytes lesions levels liarozole ligand lipid liver lutein lycopene mechanism metabolism metabolites mice mouse mutations nuclear receptors Nutr oral retinoids oxidative stress patients photoaged photosensitivity plasma proliferation protein psoriasis renal response retinaldehyde retinoic acid receptor retinoid therapy retinoid X receptor retinyl esters role RXRa serum side effects skin cancer studies suprabasal systemic retinoid tazarotene tissue topical retinoids toxicity transcription transplant treated treatment tretinoin trial tumor Vahlquist Venereol vitamin vitro vivo