Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder and Its TreatmentClare Stanford, Rosemary Tannock In this volume there is a strong emphasis on translational science, with preclinical approaches suggesting new directions for development of new treatments. Individual chapters describe how neuroimaging, neuroendocrine, genetic and behavioral studies use powerful research tools that are offering a completely new understanding of the factors that increase vulnerability to ADHD. The clinical impact of co-morbid problems, especially obesity and substance misuse, are highlighted and explain what such problems can tell us about the etiology of ADHD, more generally. Reviews of the pharmacology of established drug treatments for ADHD justify an exciting novel theory for their therapeutic actions and address questions about the effects of their long‐term use. |
Contents
Neurodevelopmental Abnormalities in ADHD | 49 |
Intraindividual Variability in ADHD and Its Implications for Research of Causal Links | 67 |
HypothalamicPituitaryAdrenocortical Axis Function in AttentionDeficit Hyperactivity Disorder | 92 |
Brain Processes in Discounting Consequences of Adolescent Methylphenidate Exposure | 113 |
Attention Deficit Hyperactivity Disorder and Substance Use Disorders | 144 |
Linking ADHD Impulsivity and Drug Abuse A Neuropsychological Perspective | 173 |
Obesity and ADHD Clinical and Neurobiological Implications | 199 |
Face Processing in Attention DeficitHyperactivity Disorder | 219 |
Quantitative and Molecular Genetics of ADHD | 238 |
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Common terms and phrases
abnormalities abuse Acad Child Adolesc activity addiction ADHD symptoms adults agonist allele amphetamine amygdala animal model Asherson associated with ADHD atomoxetine attention deficit hyperactivity attention-deficit attention-deficit/hyperactivity disorder basal basal ganglia Behav Brain behavior Biederman Biol Psychiatry Brain Res bupropion caudate Child Adolesc Psychiatry Child Psychol childhood children with ADHD clinical cocaine cognitive coloboma comorbid cortical cortisol deficit hyperactivity disorder delayed developmental diagnostic differences disorder ADHD dopamine receptor dopamine transporter dopaminergic DRD4 drug dysfunction effects emotional face processing factors Faraone SV frontal function gene genetic guanfacine hyperactivity impairment impulsivity inattention increased inhibitors Kuntsi mediated medication methylphenidate mice modafinil model of ADHD motor neonatal neural neurobiological neuronal Neurosci neurotransmitter norepinephrine nucleus accumbens obesity patients phenotypes prefrontal cortex Psychiatry regions reinforcement reuptake reward risk role RT variability Sagvolden sample serotonin Sonuga-Barke spontaneously hypertensive rat stimulants striatal striatum studies subtypes suggest Tannock task treatment versus Volkow