Calcium: A Matter of Life or Death
Elsevier, Sep 17, 2007 - Science - 584 pages
Calcium is a versatile carrier of signals regulating many aspects of cellular activity such as fertilization to create a new life and programmed cell death to end it. Calcium homeostasis is strictly controlled by channels, pumps and exchangers functioning as gates for calcium entry and release. Given that calcium is such a versatile messenger the field of calcium signaling is continuously and rapidly expanding. This book reviews the most recent developments in calcium signaling by leading experts in the field. It is a state-of-the-art summary of our present knowledge in this quickly growing field and provides insight into the impressive progress made in many areas of calcium signaling, while reminding us of how much remains to be learned.
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Acad Sci USA aequorin affinity amino acid annexin apoptosis binding Biochem Biochemistry Biol Chem Biophys C-terminal Ca2+ channels Ca2+ concentration Ca2+ release Ca2+ sensor Ca2+ signal Ca2+ stores Ca2+ transients Ca2+-binding Ca2+-dependent Ca2+/CaM calcineurin calcium calmodulin calpain calreticulin CaMKIV CaMKK Carafoli cardiac Cell Biol cellular channel activity cleavage Color Plate complex CRAC channel CREB cytokinesis cytoplasmic cytosolic domain EF-hand embryos enzymes expression function furrow gene Golgi homeostasis increased inhibition InsP3 interaction intracellular intracellular Ca2+ IP3R isoforms kinase L-type loop mechanism Mg2+ mice Mn2+ modulation molecular molecules motif mutations Natl Acad Sci neurons Neurosci NFAT oocytes oscillations pathway peptide phosphorylation Physiol plasma membrane PMCA Proc Natl Acad pump receptor region regulation regulatory residues reticulum role ryanodine ryanodine receptor RyR1 RyR2 S100 proteins sequence SERCA skeletal muscle SPCA SPCA1 SPCA2 splicing STIM1 structure subunit target transcription factors transmembrane Zhang
Page 22 - Sakuntabhai, A., Ruiz-Perez, V., Carter, S., Jacobsen, N., Burge, S., Monk, S., Smith, M., Munro, CS, O'Donovan, M., Craddock, N., Kucherlapati, R., Rees, JL, Owen, M., Lathrop, GM, Monaco, AP, Strachan, T., and Hovnanian, A., 1999b, Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease.
Page 21 - Baghdiguian, S., Martin, M., Richard, I., Pons, F., Astier, C., Bourg, N., Hay, RT, Chemaly, R., Halaby, G., Loiselet, J., Anderson, LV, Lopez de Munain, A., Fardeau, M., Mangeat, P., Beckmann, JS...
Page 21 - GI, 2000, Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus, Nat Genet.
Page 21 - Brown, EM, Gamba, G., Riccardi, D., Lombardi, M., Butters, R., Kifor, O., Sun, A., Hediger, MA, Lytton, J., and Hebert, SC (1993).
Page 21 - M., Hinokio, Y., Lindner, TH, Mashima, H., Schwarz, PE, del Bosque-Plata, L., Horikawa, Y., Oda, Y., Yoshiuchi, I., Colilla, S., Polonsky, KS, Wei, S., Concannon, P., Iwasaki, N., Schulze, J., Baier, LJ, Bogardus, C., Groop, L., Boerwinkle, E., Hanis, CL, Bell, GI (2000) Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.