The Resistance Phenomenon in Microbes and Infectious Disease Vectors: Implications for Human Health and Strategies for Containment: Workshop Summary

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National Academies Press, Apr 26, 2003 - Medical - 333 pages

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

 

Contents

SUMMARY AND ASSESSMENT
1
Introduction
19
Microbe Resistance
44
Vector Resistance
79
The Economics of Resistance
107
Factors Contributing to the Emergence of Resistance
130
Emerging Tools and Technology for Countering Resistance
159
Strategies to Contain the Development
196
APPENDIXES
231
Issues of Resistance Microbes Vectors and the Host
244
WHO Report
256
GFHR Report
274
G Forum Member Speaker and Staff Biographies
287
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