Neuropathology of Focal Epilepsies: An AtlasInterdisciplinary co-operation between epileptologists, neuroradiologists, psychologists and neurosurgeons is the most fundamental prerequisite for localising and performing targeted resections of epileptogenic foci from patients with focal therapy resistant epilepsy. Worldwide there has been a steady increase in the number of epilepsy surgery centres, and in the number of operations performed on children and babies. A systematic neuropathological description is presented here involving macroscopic and histological findings. In this book, a systematic documentation of characteristic as well as rarer alterations is presented involving 444 patients who had been operated on in Germany between 1990 and 1997 at the Bethel Epilepsy Centre in Bielefeld. It includes 257 patients with temporal lobes (TLE) and 187 patients with extratemporal epilepsy (ETE). |
Contents
Chapter I | 1 |
Chapter IV | 9 |
Temporal lobe epilepsy TLE | 17 |
15 | 41 |
Extratemporal epilepsy | 95 |
666 | 147 |
29 | 161 |
Aetiopathogenesis of focal seizures and summary | 167 |
36 | 181 |
Future perspectives | 183 |
Case reports | 223 |
37 | 254 |
Summarising table | 279 |
38 | 280 |
References | 291 |
32 | 175 |
Common terms and phrases
abnormal Age at operation amygdala astrocytosis astrogliosis balloon cells bizarre neurons cell loss cent clinical compartment coronary section cortex cortical dysplasia cortical layer defect dentate gyrus diagnosis Diagram disruption dual pathology Duration of epilepsy dysplastic EEG intensive monitoring endfolium epileptogenic extratemporal fibre fibrillary focal frontal lobe ganglioglioma GFAP GFAP preparation glial cell glioneuronal gliosis grade granular cell layer gyration gyri hemimegalencephaly hemispherectomy heterotopia hippocampal formation hippocampal sclerosis imaging infiltration leptomeningeal lesion localisation lymphocytic Macroscopic male massive mesial TL molecular layer months Neopl neoplasias nerve cells neurofilaments Neurology neuronal loss Nissl staining nodular Number of Patients occipital parahippocampal gyrus patient medical history proliferation protein receptors right temporal scar Seizure history seizure onset serial slices structures surgical synaptophysin syndrome T2-weighted Table temporal lobe epilepsy temporal lobe resection therapy-resistant tion tuberous tumour Video EEG intensive white matter