Skin Bioengineering: Techniques and Applications in Dermatology and CosmetologyPeter Elsner Non-invasive bioengineering techniques have become indispensable tools both in the development of drugs and cosmetics and in clinical dermatology. These techniques enable researchers to study the structure and function of human skin objectively and quantitatively. Recent technological developments have brought new techniques into the laboratory and the hospital, among them magnetic resonance imaging, optical coherence tomography and microdialysis. This book describes these state-of-the-art developments, details the application of skin bioengineering techniques for clinical purposes, shows their use in the testing of pharmaceutics and cosmetics and provides an overview of the design and legal aspects of skin bioengineering testing. It will be essential reading for dermatologists, cosmetologists, pharmacologists and toxicologists. |
Contents
In vivo Proton Magnetic Resonance Spectroscopy in Human Skin | 12 |
Raman Spectroscopy and Skin | 20 |
Optical Coherence Tomography of the Skin | 29 |
Examination of Stratum corneum Hydration State by Electrical | 38 |
Optothermal Measurement of Water Distribution within | 48 |
An Improved Method for the Measurement of Scalp Sebum | 61 |
State of the | 69 |
Thermal Sensory Analyzer Boon to the Study of C and A Delta Fibers | 84 |
Skin Bioengineering in Phlebology and Angiology | 129 |
Skin Bioengineering Methods in Occupational Dermatology | 145 |
Skin Bioengineering Techniques in Product Testing | 151 |
Lipid Content and Electrical Impedance | 165 |
Assessment of Skin Hydration Caused by Diapers and Incontinence | 183 |
Analysis of Cuticle Relief for Hair Photoprotection Evaluation | 196 |
Legal Situation and Study of Efficacy and Tolerability of Topical | 203 |
Correlation of in vitro and in vivo Testing | 217 |
Cutaneous Microdialysis A New Technique for the Assessment of Skin | 90 |
A New Method for Assessing in vivo in Human Subjects the Basal | 99 |
Disease Monitoring by Skin Bioengineering | 108 |
Physical Measurements for the Predictive Evaluation of the Tolerability | 235 |
Common terms and phrases
Acta Derm Venereol analysis Applications in Dermatology assessment Barel Berardesca betamethasone Bioengineering blood flow Boca Raton capacitance clinical confocal confocal microscopy Contact Dermatitis Corneometer cosmetic products CRC Press Curr Probl Dermatol curve cutaneous microdialysis deformation Derm Venereol Stockh Dermatology Dermatology and Cosmetology dermis detection device diapers disease eczema effect efficacy elastic electrical impedance Elsner epidermis evaluation frequency Gabard guidelines hair human skin hydration instruments Invest Dermatol irritant Karger layers Lévêque JL lipids mbar measurement of skin medicinal products microdialysis microscopy moisture Non-Invasive Methods normal skin optical parameters patients peroxide rate probe properties psoriasis Raman sample scanning scleroderma sebum Serup J eds skin areas Skin Bioengineering Techniques skin distensibility skin hydration skin physiology skin sites skin surface skin thickness spectroscopy standard stratum corneum stripping subjects suction systemic sclerosis temperature TEWL thermal tissue transepidermal water loss ultrasound values viscoelastic vitro vivo volunteers water content