Skin Bioengineering: Techniques and Applications in Dermatology and Cosmetology

Front Cover
Peter Elsner
Karger Medical and Scientific Publishers, Jan 1, 1998 - Medical - 250 pages
Non-invasive bioengineering techniques have become indispensable tools both in the development of drugs and cosmetics and in clinical dermatology. These techniques enable researchers to study the structure and function of human skin objectively and quantitatively. Recent technological developments have brought new techniques into the laboratory and the hospital, among them magnetic resonance imaging, optical coherence tomography and microdialysis. This book describes these state-of-the-art developments, details the application of skin bioengineering techniques for clinical purposes, shows their use in the testing of pharmaceutics and cosmetics and provides an overview of the design and legal aspects of skin bioengineering testing. It will be essential reading for dermatologists, cosmetologists, pharmacologists and toxicologists.
 

Contents

In vivo Proton Magnetic Resonance Spectroscopy in Human Skin
12
Raman Spectroscopy and Skin
20
Optical Coherence Tomography of the Skin
29
Examination of Stratum corneum Hydration State by Electrical
38
Optothermal Measurement of Water Distribution within
48
An Improved Method for the Measurement of Scalp Sebum
61
State of the
69
Thermal Sensory Analyzer Boon to the Study of C and A Delta Fibers
84
Skin Bioengineering in Phlebology and Angiology
129
Skin Bioengineering Methods in Occupational Dermatology
145
Skin Bioengineering Techniques in Product Testing
151
Lipid Content and Electrical Impedance
165
Assessment of Skin Hydration Caused by Diapers and Incontinence
183
Analysis of Cuticle Relief for Hair Photoprotection Evaluation
196
Legal Situation and Study of Efficacy and Tolerability of Topical
203
Correlation of in vitro and in vivo Testing
217

Cutaneous Microdialysis A New Technique for the Assessment of Skin
90
A New Method for Assessing in vivo in Human Subjects the Basal
99
Disease Monitoring by Skin Bioengineering
108
Physical Measurements for the Predictive Evaluation of the Tolerability
235
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