The Pituitary Body and Its Disorders: Clinical States Produced by Disorders of the Hypophysis CerebriThis work includes Cushing's description of his own method of operating on the pituitary. He was an outstanding neurological surgeon and added much to our knowledgeof the pituitary body and its disorders. |
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acromegaly activity adiposity adrenal amenorrhoea Analysis of Hypophyseal animals anterior lobe appear assimilation limit bitemporal hemianopsia blood pressure carbohydrate carbohydrate tolerance cerebrospinal changes choked disc Chromophobe struma clinical colloid condition cranial cyst deficiency disease disturbances ductless glands dyspituitarism enlarged sella epiphyseal exophthalmos experimental extreme fluid functional gigantism glandular insufficiency glycosuria grams growth headaches histological hydrocephalus hyperplasia hypertrichosis hypophyseal hypophyseal struma Hypophyseal Symptoms hypopituitarism increase infantilism infundibular injection interpeduncular intracranial lævulose lesion malady manifestations marked measure negative neighborhood symptoms normal observed occur operation optic atrophy overgrowth pars intermedia pars nervosa patient pigmentation pineal pituitary body polyuria possible posterior lobe posterior lobe extract pounds pressure symptoms primary pulse secondary sella turcica sellar decompression sexual shown skeletal skin slight struma subtemporal decompression sugar tolerance Surgical syndrome tendency thermic reaction thyroid tion tissue transphenoidal tumor uncinate ventricle vision vomiting weight whole gland X-ray
Popular passages
Page 239 - The primary defect usually first involves the color boundaries alone in one upper temporal quadrant. This is followed by a more or less complete temporal hemiachromatopsia, possibly with a "slant" in the upper temporal form field, which gradually spreads downward until most of the temporal field is involved. In all cases the color fields are involved first: the form fields later. The macular area is often spared for a long time, but finally it becomes implicated in turn, first in its temporal half....
Page 11 - Normal posterior lobe activity is essential to effective carbohydrate metabolism. An intravenous injection of posterior lobe extract produces glycogenolysis, and its continued administration in excessive amounts leads to emaciation. A diminution of posterior lobe secretion occurring in certain conditions of hypopituitarism (whether experimentally produced as the result of disease) leads to an acquired tolerance for sugars, with the, resultant accumulation of fat.
Page 238 - It is safe to say that the amblyopia associated with a primary atrophy more often represents a physiological block to light impulses than an actual destruction of the nerves...
Page 19 - Group II. Cases in which the neighborhood manifestations are pronounced but the glandular symptoms are absent or inconspicuous. "Group III. Cases in which neighborhood manifestations are absent or inconspicuous though glandular symptoms are pronounced and unmistakable. "Group IV.
Page iii - If the reader coinBides with the text he will harbor the opinion that there is every reason to believe that cases of clinically recognizable pituitary disease are at least as common as are cases of clinically recognizable thyroid disease.
Page 19 - Group I. Cases of dyspituitarism in which not only the signs indicating distortion of neighboring structures but also the symptoms betraying the effects of altered glandular activity are outspoken.
Page 252 - ... to persistence of the thymus. "Hypopituitarism causes skeletal undergrowth which occurs when glandular insufficiency begins before the full stature is attained. When lack of activity begins before adolescence the skeleton has the feminine type." "We have attributed this particular symptom complex of adiposity, high sugar tolerance, subnormal temperature, slowed pulse, asthenia and drowsiness to a secretory deficiency of the posterior lobe; and a further argument in favor of this view is the reverse...
Page 13 - ... hypophysectomized adult canines deprived of all but a fragment of the pars anterior disclosed a clinical syndrome with adiposity, increased sugar tolerance, lowered body temperature and reversive sexual changes as its chief features. Later experiences, with the production of corresponding...
Page 19 - Cases with a polyglandular syndrome in which the functional disturbances on the part of the hypophysis are merely one and not a predominant feature of a general involvement of the ductless glands.
Page 19 - ... ossification of the epiphyses — typus Launois; resulting in acromegaly when it is of later occurrence — typus Marie) ; (2) those in which the clinical...