The Mechanism and Management of Corneal Graft RejectionBasic immunology relating to corneal graft rejection is presented in this book. All aspects of corneal graft rejection, from the historical perspective to the diagnosis, treatment and prevention of corneal graft rejection, are discussed. The author includes controversial topics such as the roles of systemic immunosuppressant agents and tissue matching. |
Contents
An historical review of corneal grafting | 1 |
An overview of transplantation immunology | 5 |
Corneal transplantation immunology | 21 |
Risk factors in penetrating keratoplasty | 43 |
Tissue typing and matching in corneal transplantation | 63 |
The diagnosis of corneal graft rejection | 77 |
The prevention of corneal graft rejection | 85 |
The treatment of corneal graft rejection | 91 |
The role of cyclosporin in preventing corneal graft rejection | 103 |
Future trends in managing corneal graft rejection | 127 |
Common terms and phrases
ACAID activation anterior chamber antigen presentation Arch Ophthalmol blood CCTS CD4+ class II antigens clinical Collaborative Corneal Transplantation corneal endothelium Corneal Graft Failure corneal graft rejection corneal graft survival corneal transplantation Corneal Transplantation Studies corticosteroids Coster DJ crossmatch CSA group cyclosporin cytokines cytotoxic T cells dose effect endothelial cells endothelial rejection epithelial epithelium failure from rejection Foulks GN graft reaction helper T cells high-risk corneal high-risk keratoplasty histocompatibility HLA-A human corneal immune response Immunol immunological privilege immunosuppressive incidence of rejection Invest Ophthalmol keratitis keratoconus Langerhans cells long CSA group lymphocytes macrophages molecules monoclonal antibody Niederkorn Niederkorn JY Ophthalmol Vis Sci Ophthalmology penetrating keratoplasty postoperative preoperative previous graft quadrants rabbits recipient regimen rejection episode rejection process reported risk factors role Sanfilippo steroids stromal surgery sutures systemic CSA tion tissue topical corticosteroids topical CSA topical steroids Trans Transplant Proc treatment UV-B vascularized corneas vessels