Adhesion Molecules in Health and DiseaseProvides an overview of the structure, transcription regulation and binding characteristics of cellular adhesion molecules and their ligands in the maintenance of function, immunological reactions and inflammatory processes with organ systems. The text examines the role of adhesion molecules in biological processes such as morphogenesis, blood coagulation, tumour metastasis, bone tissue remodelling and transplant rejection. |
Contents
Strategies to Inhibit Cellular Adhesion Molecules | 55 |
Measurement of Soluble Adhesion Molecules | 87 |
Circulating Adhesion Receptors in Health | 123 |
Adhesion Molecules as Signal Transduction | 155 |
Adhesion Molecules as Mechanoreceptors | 181 |
Morphogenesis of Epithelial Cells | 205 |
Adhesion Molecules in Immunoregulation | 223 |
Regulation of Endothelial Selections | 237 |
Adhesion Molecules in Bone Remodeling | 427 |
Adhesion Molecules in Tumor Growth and Metastasis | 445 |
Adhesion Molecules in Reperfusion Injury | 483 |
Cellular Adhesion Molecules in Neurology | 503 |
Adhesion Molecules in Inflammatory Lung Injury | 523 |
Role of Adhesion Molecules in Intestinal | 539 |
Adhesion Molecules in Rheumatoid Arthritis | 561 |
Adhesion Molecules in the Immunopathogenesis | 589 |
Role of Chemoattractants in Neutrophil Recruitment | 257 |
Adhesion Molecules in LymphocyteMediated | 289 |
Structure and Function | 313 |
Use of Host Adhesion Molecules by Infectious Agents | 347 |
Modulation of Leukocyte Trafficking in Infectious | 381 |
Adhesion Molecules in Atherosclerosis | 401 |
Common terms and phrases
Acad Sci USA activation acute adhe adherence adhesion receptors allograft antigen arthritis binding Biol Chem blood Butcher EC cadherin carbohydrate cell adhesion molecule Cell Biol 1992 cell surface cell-cell cellular chemoattractants circulating Clin Invest cytes cytokines cytoskeleton disease E-cadherin endothelial cells endothelium epithelial cells expression extracellular matrix factor fibronectin function gene glycoprotein graft human immune immunoglobulin Immunol increased induced infection infiltration inflammation inflammatory inhibited integrin interactions intercellular adhesion molecule-1 interleukin-8 ischemia kidney kinase lectin leukocyte adhesion leukocyte rolling levels ligand lung injury lymph node lymphocytes macrophages MAdCAM-1 mechanisms mediated membrane mice migration molecular monoclonal antibody monocytes Natl Acad Sci neutrophils osteoclasts P-selectin pathway patients peptides peritoneal phosphorylation plasma platelets Proc Natl Acad protein rabbits recruitment regulation renal reperfusion response role selectin serum sialyl sion skin soluble specific Springer stimulation studies subunit synovial T-cell tion tissue Transplantation tumor tyrosine upregulation venules vitro vivo