Vasopressin and Oxytocin: From Genes to Clinical Applications

Front Cover
D. Poulain, S. Oliet, D. Theodosis
Elsevier, Oct 24, 2002 - Science - 392 pages
The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system.


Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.

 

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Contents

cellspecific gene expression in the hypothalamoneurohypophysial system
1
Chapter 2 Estrogen modulates oxytocin gene expression in regions of the rat supraoptic and paraventricular nuclei that contain estrogen receptorβ
15
Chapter 3 Shortterm modulation of GABAA receptor function in the adult female rat
31
modulators of oxytocin receptor function
43
Chapter 5 Central vasopressin systems and steroid hormones
57
Chapter 6 Regulation of renal salt and water transporters during vasopressin escape
75
cellular targets for modulation of osmosensitivity in supraoptic neurons
85
key elements of the regulation of neuronal electrical and secretory activity
95
a model system to characterize cisacting elements and transacting factors involved in dendritic mRNA sorting
211
Chapter 17 Dendritic action potentials in magnocellular neurons
225
Chapter 18 Modulation of synaptic transmission by oxytocin and vasopressin in the supraoptic nucleus
235
Chapter 19 The active role of dendrites in the regulation of magnocellular neurosecretory cell behavior
247
Chapter 20 Cardiovascular regulation of supraoptic vasopressin neurons
257
Chapter 21 The central vasopressinergic system in experimental left ventricular hypertrophy and dysfunction
275
Chapter 22 Cardiovascular effects of oxytocin
281
focus on cardiovascular and renal risk reduction
289

Chapter 9 Functional synaptic plasticity in hypothalamic magnocellular neurons
113
Chapter 10 Postsynaptic GABAB receptors in supraoptic oxytocin and vasopressin neurons
121
Chapter 11 Neurohypophyseal hormones in the integration of physiological responses to immune challenges
127
interactions with the hypothalamopituitaryadrenal axis
147
Chapter 13 Expression of human vasopressin and oxytocin receptors in Escherichia coli
163
Chapter 14 Molecular pharmacology and modeling of vasopressin receptors
179
development of selective and orally active V1a V2 and V1b receptor ligands
197
Chapter 24 Oxytocin in parturition of guinea pigs humans and other species
299
Chapter 25 Oxytocin vasopressin and atrial natriuretic peptide control body fluid homeostasis by action on their receptors in brain cardiovascular syst...
309
Chapter 26 Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer
329
Chapter 27 The vasopressin receptor of corticotroph pituitary cells
345
Chapter 28 Involvement of oxytocin and vasopressin in the pathophysiology of preterm labor and primary dysmenorrhea
359
Subject Index
367
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Page 12 - Eberwine, J., Yeh, H., Miyashiro, K., Cao, Y., Nair, S., Finnell, R., Zettel, M., and Coleman, P. (1992) Analysis of gene expression in single live neurons. Proc. Natl. Acad. Sci. USA 89, 3010-3014.

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