Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Front Cover
Prashant Kesharwani
Academic Press, Jan 26, 2019 - Medical - 340 pages

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions.

  • Provides an overview of an array of nanotechnology-based drug delivery systems
  • Examines the design, synthesis and application of different nanocarriers in drug and gene delivery
  • Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers
 

Contents

1 An Overview of the Anatomy and Physiology of the Lung
1
2 An Overview Current Challenges of Drug Resistance and Targeting Metastasis Associated With Lung Cancer
21
3 Overexpressed Receptors and Proteins in Lung Cancer
39
4 Polymeric NanoparticleBased DrugGene Delivery for Lung Cancer
77
5 Solid Lipid NanoparticleBased Drug Delivery for Lung Cancer
95
6 LiposomeBased Drug Delivery for Lung Cancer
123
7 DendrimerBased Nanocarriers in Lung Cancer Therapy
161
8 Polymeric Micelles in Management of Lung Cancer
193
9 Nanoemulsions as Effective Carriers for the Treatment of Lung Cancer
217
10 NanomedicineBased Inhalation Treatments for Lung Cancer
249
11 Toward the Development of a Novel Diagnostic NanoImaging Platform for Lung Cancer
269
12 HydrogelBased Drug Delivery for Lung Cancer
293
13 Quantum DotBased Drug Delivery for Lung Cancer
311
Index
327
Back Cover
335
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About the author (2019)

Dr. Prashant Kesharwani is working as an assistant professor of pharmaceutics at the School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 300 international publications in well-reputed journals and more than 20 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also a receipt of several internationally acclaimed awards such as the most prestigious “Ramanujan Fellowship Award from the Science and Engineering Research Board, Government of India. He actively participates in outreach and scientific dissemination for the service of the wider community.

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