Q Fever: The Disease, Volume 1
This fascinating book describes the history, and epidemiology in both man and animals, and clinical features of this zoonosis. It reveals detailed information pertaining to the basic science aspects of the interaction of Coxiella burnetii, the etiologic agent of Q (Query) fever, with the host and the immune response of the host to this unique pathogen. This one-of-a-kind work uses the rules of epidemiological evidence to determine whether or not Coxiella burnetii is a perinatal pathogen for man. This interesting, easy-to-understand text concludes with chapters dealing with the antibiotic susceptibility of Coxiella burnetii and the studies that resulted in a vaccine that now can be used to prevent this infection. This volume is an absolute must for all microbiologists, respirologists, infectious disease physicians and veterinarians.
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TABLE OF CONTENTS
Naming of an Organism
Coxiellosis QFever in Animals
Immune Response to Coxiella burnetii Infection
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abattoir abortion acute Q fever aerosol agent alveolar animals antibiotic antibody antigen arrows Aust bacterial biopsy blood burnetii antigen burnetii infection cats cattle cell-mediated immunity cellular chronic Q fever clinical cows Coxiella burnetii coxiellosis dairy Derrick developed Q fever diagnosis dose epidemiology epidemiology of Q erythromycin febrile fever endocarditis fever hepatitis fever infection fever pneumonia fever studies fever vaccine Figure goats granulomas guinea pigs hospital host cells human illness immune response Immunol infectious foci inflammatory inoculation isolated Khavkin laboratory Legionella lesions liver lymphocytes lymphokines macrophages mice Microbiol microorganisms milk mononuclear Mycoplasma Mycoplasma pneumoniae Nine Mile normal Nova Scotia observed occurred organism outbreak of Q pathogen Pathol patients with Q phagocytes phagolysosomes placenta pneumophila Public Health Rep receptors reported respiratory Rickettsia Rickettsial Diseases rifampin serological seropositive serum sheep skin test specific spleen splenomegaly strains tetracycline therapy ticks tissue titers transmission vacuole valve Yes Yes Yes yolk sac