Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes

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Manuela E Gomes, Rui L. Reis, Márcia T Rodrigues
Academic Press, Aug 8, 2015 - Medical - 470 pages

Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies.

Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices.

Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field.

  • Provides an overview of tendon biology, disease, and tissue engineering approaches
  • Presents modern, alternative approaches to developing functional tissue solutions discussed
  • Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine
  • Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices
  • Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field
 

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Contents

SECTION 2 Pathologies and Repairof Tendons
111
SECTION 3 Tendon Regenerative Medicine Approaches
185
SECTION 4 ScaffoldsBased Approaches
223
SECTION 5 Tendon Tissue Engineering
257
INDEX
439
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About the author (2015)

Prof. Rui L Reis is the Vice-President for Research and Innovation of University of Minho (Portugal), Director of the 3B’s Research Group, I3Bs - Institute for Biomaterials, Biodegradables and Biomimetics, and Director of ICVS/3B ́s Associate Laboratory, both at University of Minho (Portugal). He is also the CEO of the European Institute of TERM, the Coordinator of Discoveries Centre for Regenerative and Precision Medicine, and the Global Past-President of Tissue Engineering and Regenerative Medicine International Society (TERMIS). He is a recognized world expert in the TERM and biomaterials fields, has edited several books and has more 1200 publications and around 70 patents. He co-founded several companies that raised private investments. He has been awarded several important international prizes, including among others the Jean Leray and George Winter Awards (ESB), the Clemson Award (SFB) and TERMIS-EU Awards (i) for contributions to the literature and (ii) the lifetime achievement, and recently the UNESCO- International Life Sciences Award and the IET A. F. Harvey Engineering Research Prize.

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