Hematology: Basic Principles and PracticeHematology, 6th Edition encompasses all of the latest scientific knowledge and clinical solutions in the field, equipping you with the expert answers you need to offer your patients the best possible outcomes. Ronald Hoffman, MD, Edward J. Benz, Jr., MD, Leslie E. Silberstein, MD, Helen Heslop, MD, Jeffrey Weitz, MD, John Anastasi, MD, and a host of world-class contributors present the expert, evidence-based guidance you need to make optimal use of the newest diagnostic and therapeutic options. Make confident, effective clinical decisions by consulting the world's most trusted hematology reference. Access the complete contents online at www.expertconsult.com, with a downloadable image collection, regular updates, case studies, patient information sheets, and more. Apply all the latest knowledge on regulation of gene expression, transcription splicing, and RNA metabolism; pediatric transfusion therapy; principles of cell-based gene therapy; allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome in adults; hematology in aging; and much more, thanks to 27 brand-new chapters plus sweeping updates throughout.Find the information you need quickly and easily thanks to a completely reworked organization that better reflects today's clinical practice.Visualize clinical problems more clearly with new and updated images that reflect the pivotal role of hematopathology in modern practice.Benefit from the experience and fresh perspective of new editor Dr. Jeffrey Weitz, Professor of Medicine at McMaster University School of Medicine and Executive Director of the Thrombosis and Atherosclerosis Research Institute in Ontario. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued. |
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Contents
II Cellular Basis of Hematology | 77 |
III Immunologic Basis of Hematology | 171 |
IV Disorders of Hematopoietic Cell Development | 257 |
V Red Blood Cells | 405 |
VI NonMalignant Leukocytes | 639 |
VII Hematologic Malignancies | 721 |
VIII Comprehensive Care of Patients with Hematologic Malignancies | 1375 |
Common terms and phrases
abnormalities activation adhesion amino acid anemia antibody antigen apoptosis associated autoimmune binding Biol Blood bone marrow cancer cell cycle cellular chain chemokine chromosome clinical complement complex CXCR4 cyclin cytokine cytoplasmic deficiency defined dendritic cells differentiation disease domain encoding endothelial cells enzymes EPOR erythroblasts erythroid erythropoiesis fetal first function G-CSF GATA1 gene expression genetic genome growth factor hematologic hematopoietic stem cells HSPC human identified Immunol increased induced infection inhibition inhibitors integrins interactions intracellular kinase leukemia leukocyte ligand lineage lymphocytes lymphoid macrophages maturation mechanisms mediated Medicine megakaryocyte membrane mice molecular molecules mouse mRNA murine mutations myeloid natural killer neutrophil niche NK cells normal pathogens pathway patients peptide phenotype phosphorylation platelet progenitor cells proliferation protein receptor regulation role sequence signaling specific stromal structure syndrome T-cell T—cell target therapy thrombocytopenia tion tissues transcription factors transplantation tumor tyrosine vascular vitro vivo