Cardiac Adaptations: Molecular MechanismsBohuslav Ostadal, Naranjan S. Dhalla This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities. |
Other editions - View all
Cardiac Adaptations: Molecular Mechanisms Bohuslav Ostadal,Naranjan S. Dhalla No preview available - 2014 |
Cardiac Adaptations: Molecular Mechanisms Bohuslav Ostadal,Naranjan S. Dhalla No preview available - 2012 |
Common terms and phrases
activity adenosine adenylyl cyclase adult angiogenesis angiotensin aortic apoptosis Appl Physiol arterial athletes autophagy b-AR Biochem Biol Ca2+ CaMKII Cardiac Adaptations cardiac function cardiac hypertrophy cardiac remodeling cardiomyocytes Cardiovasc Res cardiovascular cellular chronic hypoxia Circ Circ Res Circulation Clin collagen contractile coronary decreased Dhalla diastolic disease dysfunction effects of exercise endurance training eNOS estrogen exercise training extracellular fatty acid fetal fibroblasts fibrosis gene expression growth factor Heart Circ Physiol heart failure hemodynamic hypertension hypoxia increased induced infarction inhibition inhibitors ischemia ischemic left ventricular levels mechanisms metabolism mice miRNAs mitochondrial mitral regurgitation Mol Cell Cardiol molecular myocardial myocardial infarction myocardium myocytes overexpression oxidative stress oxygen P-TEFb patients Pharmacol phosphorylation Physiol Heart Circ physiological pressure overload protein kinase pulmonary rat heart receptor reduced regulation response role signaling pathways SIRT1 SIRT3 sirtuins skeletal muscle Springer Science+Business Media studies systolic transcription factors upregulation vascular VEGF ventricle volume overload