Applied Immunohistochemistry in the Evaluation of Skin NeoplasmsJose A. Plaza, Victor G. Prieto This book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to considerable diagnostic uncertainty. The book reviews in detail the sensitivity and specificity of commonly available antibodies and their pattern of immunostaining. readers will learn when to order antibodies and how to interpret findings. In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. The text is complemented by a wealth of superb images. Helpful histograms and algorithms are included, and clear guidance is provided on the application and interpretation of less commonly used antibodies and immunostains. Applied Immunohistochemistry in the Evaluation of Skin Neoplasms will serve as an extremely valuable resource for practicing dermatopathologists and pathologists. |
Contents
Adnexal Neoplasms | 25 |
Immunohistology of Cutaneous Metastases and Its Simulators | 100 |
Immunohistology of Mesenchymal Neoplasms | 116 |
Immunohistology of Cutaneous Lymphoma | 205 |
Immunohistology of Melanocytic Lesions | 309 |
Other editions - View all
Applied Immunohistochemistry in the Evaluation of Skin Neoplasms Jose A. Plaza,Victor G. Prieto No preview available - 2016 |
Applied Immunohistochemistry in the Evaluation of Skin Neoplasms Jose A. Plaza,Victor G. Prieto No preview available - 2018 |
Common terms and phrases
actin activity addition analysis antibody apocrine appearance areas associated atypical B-cell lymphoma basal cell carcinoma benign Blood Cancer cell carcinoma changes chromosome Clin clinical clonal common compared Cutan Pathol cytoplasm demonstrate dermal Dermatol Dermatopathol dermis described detected differential diagnosis diffuse disease distinct distinguish endothelial epidermal epithelial et al expression factor findings FISH follicular frequent gene genetic glands granular growth histiocytic histologic histopathologic immunohistochemical Immunohistochemistry increased infiltrate involvement lesions leukemia loss lymph node lymphocytes malignant markers melanocytic melanoma Merkel cell carcinoma metastatic mitotic molecular multiple mutations negative neoplasms nerve nevi nevus noma nuclear nuclei occur origin patients pattern peripheral positive present primary cutaneous proliferation protein rare receptor reported sarcoma sebaceous sebaceous adenomas seen sensitivity sheath similar skin specific staining Surg Pathol syndrome T-cell tion tissue tumor tumor cells typically usually variant vascular